This study investigated the effect of end-of-life care at home on thoughts of patients’ families. Semi-structuredinterviews were conducted with primary caregivers（N=16）with experience in giving end-of-life care at home, and of gettingthe cooperation from relevant organizations. The contents of interviews, which were mainly about reasons why they couldprovide end-of-life care at home, were recorded and documented, and analyzed through the Grounded Theory Approach. Theresults indicated that the families had the following four types of thoughts: satisfaction after giving end-of-life care, difficultiesin providing care, regrets, and making good use of the experience in the future. It was indicated that the families had bothnegative and positive thoughts about end-of-life care at home. The importance of supporting such families is suggested so thatsatisfaction after giving end-of-life care would exceed the difficulties, as well as regrets about providing care.