Journal Article Fluid Dynamics of Single-needle Dialysis in an Experimental Model
Fluid Dynamics of Single-needle Dialysis in an Experimental Model

Hans, Scholz  ,  Yasushi, Matsushita  ,  Ulf, Krueger  ,  Matthias, Wunsch  ,  Uwe, Lorenz  ,  Karen, Petzold  ,  Djamal, Zidane  ,  Department Of Vascular Surgery, Queen Elisabeth Hospital  ,  Department Of Cardiac And Vascular Surgery, Dokkyo Medical University, Nikko Medical Center  ,  Department Of Vascular Surgery, Queen Elisabeth Hospital  ,  Department Of Vascular Surgery, Queen Elisabeth Hospital  ,  Department Of Vascular Surgery, Queen Elisabeth Hospital  ,  Department Of Vascular Surgery, Queen Elisabeth Hospital  ,  Department Of Vascular Surgery, Queen Elisabeth Hospital

43 ( 1 )  , pp.1 - 4 , 2016-03-25
ISSN:03855023
NCID:AA00629581
Description
Background:Acceptance has grown for single-needle dialysis when a vascular access is not suited for the insertion of two needles. Its impact on flow patterns was unknown. Methods:We produced transparent life-size models of arteriovenous(AV)fistulas and AV grafts that we placed into a pulsatile flow system to examine flow characteristics during simulated dialysis cycles. For this purpose we injected dye, and recorded and analyzed the resulting flow patterns using suitable software tools. Results:There is a definite flow reversal during the arterial phases in both AV fistulas and -less pronounced-in AV grafts leading to flow oscillations. Conclusion:Flow oscillations initiate subintimal hyperplasia possibly leading to stenoses in vivo. Reversal of the flow direction may also cause steal phenomena in the poorly perfused distal extremity. Single-needle dialysis should therefore be avoided if possible.
Full-Text

https://dmu.repo.nii.ac.jp/?action=repository_action_common_download&item_id=1288&item_no=1&attribute_id=21&file_no=1

Number of accesses :  

Other information