紀要論文 Controlling Nutritional Status is Useful for Predicting Postoperative Complications in very Elderly Patients with Colorectal Cancer: A Retrospective Study

SAITO Akira:筆頭著者:責任著者  ,  MURAKAMI Masahiko  ,  WATANABE Makoto  ,  OZAWA Yoshiaki  ,  TOMIOKA Kodai  ,  KOMOTO Masahiro  ,  KITAJIMA Tetsuya  ,  YAMAZAKI Kimiyasu  ,  FUJIMORI Akira  ,  OTSUKA Koji  ,  AOKI Takeshi

28 ( 4 )  , pp.317 - 325 , 2016-12 , Showa University Society
ISSN:0915-6380
内容記述
Controlling Nutritional Status (CONUT) is an efficient tool for early detection of malnutrition, measured using two biochemical parameters (serum albumin and total cholesterol) and one immune indicator (total lymphocyte count). The aim of this study was to define the efficacy of CONUT for predicting postoperative complications in very elderly patients with colorectal cancer. This study enrolled 52 patients aged 85 years or older with colorectal cancer for whom we were able to measure CONUT before surgery, conducted at the Department of Gastroenterological and General Surgery of Showa University Hospital in Japan between January 2010 and December 2014. The patients were subdivided into those with complications (Group C, n=9) and those with no complications (Group NC, n=43), and then were retrospectively compared for clinical characteristics, CONUT, and surgical outcomes. Multivariate analysis was finally performed to identify the risk factors of complications. The percentage of patients with a CONUT score of 5 or more in Group C was significantly greater than that in Group NC (7 vs. 12 patients, 77.8% vs. 27.9%, P=0.0079). No other significant difference was observed in the clinical characteristics between Group C and Group NC. Multivariate analysis identified CONUT score as the only significant predictor of complications in this patient cohort (odds ratio=1.374; 95% confidence interval, 1.019-1.949; P=0.0366). Our study suggests that CONUT score is predictive of postoperative complications in very elderly patients with colorectal cancer.
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