Departmental Bulletin Paper Efficacy and Safety of an Ultrasonically Activated Device for Sealing the Bile Ducts During Liver Resection

AOKI Takeshi:筆頭著者:責任著者  ,  MURAKAMI Masahiko  ,  KOIZUMI Tomotake  ,  ENAMI Yuta  ,  KOIKE Reiko  ,  FUJIMORI Akira  ,  KUSANO Tomokazu  ,  MATSUDA Kazuhiro  ,  YAMADA Kosuke  ,  NOGAKI Koji  ,  WADA Yusuke  ,  HAKOZAKI Tomoki  ,  TOMIOKA Kodai  ,  GOTO Satoru  ,  YOSHITAKE Osamu  ,  WATANABE Makoto  ,  OTSUKA Koji

27 ( 3 )  , pp.185 - 192 , 2015-09 , Showa University Society
The use of ultrasonically activated devices (USADs) in hepatic resections may be associated with an increased rate of complications, such as postoperative bile leaks. Nonetheless, the safety of USADs for sealing bile ducts during liver surgery has not yet been established. The purpose of this study was to assess the efficacy of a USAD for sealing bile ducts. In animal experiments, the common bile duct of ten anesthetized dogs was individually occluded using a USAD. Additionally, using the prospective liver surgery database from a single institution, we identified 45 consecutive patients who underwent hepatic resection using a USAD (USAD group) and 45 similar patients who underwent hepatic resection without the use of a USAD (NUSAD group). In the occluded and harvested canine bile ducts, the mean burst pressure was 280mmHg, and the lumen of the bile duct was completely sealed morphologically. In the clinical study, there was no significant difference in postoperative mortality or complications between the two groups, and biliary leakage was observed in only one patient (0.7%) in the USAD group. These data demonstrate that the USAD is a safe, efficient, and practical instrument for use during liver surgery to achieve complete hemobiliary stasis.

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