Journal Article Feasibility of magnetic resonance redox imaging at low magnetic field: Comparison at 1 T and 7 T

Nakamura, Mizuki  ,  Shibata, Sayaka  ,  Yamasaki, Toshihide  ,  Ueno, Megumi  ,  Nakanishi, Ikuo  ,  Ken-ichiro, Matsumoto  ,  Kamada, Tadashi  ,  Ken-ichi, Yamada  ,  Aoki, Ichio

9 ( 8 ) 2017-09 , e-Century Publishiong Corporaqtion
ISSN:1943-8141
Description
The effect of different static magnetic field strength, 1 or 7 T, on a quality of nitroxyl radical based magnetic resonance redox imaging (MRRI) was demonstrated. The nitroxyl radical based T1-weighted signal enhancement ratio was higher at a 1 T imager compare to a 7 T imager when scanning was carried out using a similar gradient echo sequence. The gradient echo scanning at 7 T was sensitive to movement and/or flux of the sample solution, which would be resulted in distortion of baseline T1 weighted signal. No such wobbling signal was observed when the experiment was done at the 1 T. In vivo nitroxyl decay curve was similar at 1 and 7 T. Nitroxyl radical based redox imaging could be enough performed on clinically popular 1 T.

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