Journal Article Assessment of neuroinflammation in a mouse model of obesity and β-amyloidosis using PET.

Barron, Anna  ,  Tokunaga, Masaki  ,  Ming-Rong, Zhang  ,  Ji, Bin  ,  Suhara, Tetsuya  ,  Higuchi, Makoto

13 ( 1 )  , pp.221-1 - 221-14 , 2016-08
Obesity has been identified as a risk factor for cognitive decline and Alzheimer's disease (AD). The aim of this study was to investigate the effect of obesity on neuroinflammation and cerebral glucose metabolism using PET in a mouse model of β-amyloidosis and determine the relationship between these PET imaging biomarkers, pathogenic changes, and functional outcomes.

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