学術雑誌論文 Development of a small single-ring OpenPET prototype with a novel transformable architecture

Tashima, Hideaki  ,  Yoshida, Eiji  ,  Inadama, Naoko  ,  Nishikido, Fumihiko  ,  Nakajima, Yasunori  ,  Wakizaka, Hidekatsu  ,  Shinaji, Tetsuya  ,  Nitta, Munetaka  ,  Kinouchi, Shoko  ,  Suga, Mikio  ,  Haneishi, Hideaki  ,  Inaniwa, Taku  ,  Yamaya, Taiga

61 ( 4 )  , pp.1795 - 1809 , 2016-02 , IOP Publishing
ISSN:0031-9155
内容記述
The single-ring OpenPET (SROP), for which the detector arrangement has a cylinder shape cut by two parallel planes at a slant angle to form an open space, is our original proposal for in-beam PET. In this study, we developed a small prototype of an axial-shift type SROP (AS-SROP) with a novel transformable architecture for a proof-of-concept. In the AS-SROP, detectors originally forming a cylindrical PET are axially shifted little by little. We designed the small AS-SROP prototype for 4-layer depth-of-interaction detectors arranged in a ring diameter of 250 mm. The prototype had two modes: open and closed. The open mode formed the SROP with the open space of 139 mm and the closed mode formed a conventional cylindrical PET. The detectors were simultaneously moved by a rotation handle allowing them to be transformed between the two modes. We evaluated the basic performance of the developed prototype and carried out in-beam imaging tests in the HIMAC using 11C radioactive beam irradiation. As a result, we found the open mode enabled in-beam PET imaging at a slight cost of imaging performance; the spatial resolution and sensitivity were 2.6 mm and 5.1% for the open mode and 2.1 mm and 7.3% for the closed mode. We concluded that the AS-SROP can minimize the decrease of resolution and sensitivity, for example, by transforming into the closed mode immediately after the irradiation while maintaining the open space only for the in-beam PET measurement.

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