Journal Article Increase in [18F]-Fluoroacetate Uptake in Patients With Chronic Hemodynamic Cerebral Ischemia.

Yamauchi, Hiroshi  ,  Kagawa, Shinya  ,  Kishibe, Yoshihiko  ,  Takahashi, Masaaki  ,  Nishii, Ryuichi  ,  Mizuma, Hiroshi  ,  Takahashi, Kazuhiro  ,  Onoe, Hirotaka  ,  Higashi, Tatsuya

46 ( 9 )  , pp.2669 - 2672 , 2015-09 , Lippincott Williams & Wilkins
[18F]-fluoroacetate ((18)F-FACE) can be used for evaluating glial cell metabolism. Experimental studies have shown an increase in (18)F-FACE uptake in rodent models of cerebral ischemia. The aim of this study was to determine whether (18)F-FACE uptake is increased in the noninfarcted cerebral cortex in patients with hemodynamic ischemia owing to atherosclerotic internal carotid artery or middle cerebral artery disease.

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