Journal Article Comparison of 18F-fluorodeoxyglucose positron emission tomography (FDG PET) and cardiac magnetic resonance (CMR) in corticosteroid-naive patients with conduction system disease due to cardiac sarcoidosis.

Ohira, Hiroshi  ,  H. Birnie, David  ,  Pena, Elena  ,  Bernick, Jordan  ,  Mc Ardle, Brian  ,  Leung, Eugene  ,  A. Wells, George  ,  Yoshinaga, Keiichiro  ,  Tsujino, Ichizo  ,  al, et

43 ( 2 )  , pp.259 - 269 , 2015-11 , Springer International Publishing AG
Purpose Cardiac sarcoidosis (CS) is a cause of conductionsystem disease (CSD). 18F-Fluorodeoxyglucose-positronemission tomography (FDG PET) and cardiac magnetic resonance(CMR) are used for detection of CS. The relative diagnosticvalue of these has not been well studied. The aimwas tocompare these imaging modalities in this population.Methods We recruited steroid-naive patients with newly diagnosedCSD due to CS. All CS patients underwent both imagingstudies within 12 weeks of each other. Patients wereclassified into two groups: group A with chronic mild CSD(right bundle branch block and/or axis deviation), and group Bwith new-onset atrioventricular block (AVB, Mobitz type II orthird-degree AVB).Results Thirty patients were included. Positive findings onboth imaging studies were seen in 72 % of patients (13/18)in group A and in 58 % of patients (7/12) in group B. Theremainder (28 %) of the patients in group Awere positive onlyon CMR. Of the patients in group B, 8 % were positive onlyon CMR and 33 % were positive only on FDG PET. Patients

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