Journal Article Preclinical evaluation of 2-amino-2-[11C]methyl-butanoic acid as a potential tumor-imaging agent in a mouse model.

Suzuki, Chie  ,  Tsuji, Atsushi  ,  Kato, Koichi  ,  Sudo, Hitomi  ,  Ming-Rong, Zhang  ,  Saga, Tsuneo

36 ( 11 )  , pp.1107 - 1112 , 2015-11 , Lippincott Williams & Wilkins
C-labeled 2-amino-2-methyl-butanoic acid (Iva) was previously reported to provide high tumor uptake; however, the pharmacokinetic properties of C-labeled Iva have not been characterized. In the present study, we evaluated the potential of [C]Iva as a PET probe for tumor imaging.

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