||Preclinical evaluation of 2-amino-2-[11C]methyl-butanoic acid as a potential tumor-imaging agent in a mouse model.
Suzuki, Chie ,
Tsuji, Atsushi ,
Kato, Koichi ,
Sudo, Hitomi ,
Ming-Rong, ZhangSaga, Tsuneo
Nuclear medicine communications
1112 , 2015-11 , Lippincott Williams & Wilkins
C-labeled 2-amino-2-methyl-butanoic acid (Iva) was previously reported to provide high tumor uptake; however, the pharmacokinetic properties of C-labeled Iva have not been characterized. In the present study, we evaluated the potential of [C]Iva as a PET probe for tumor imaging.