Departmental Bulletin Paper Influence of Freezing of Gait on Quality of Life in Patients with Parkinson’s disease

Mitsuaki, ISHII  ,  Kohei, OKUYAMA

12pp.1 - 10 , 2018-03-01 , 佛教大学保健医療技術学部
Purpose: Coping with distress in daily life due to freezing of gait (FOG) is one of the unmet needs for patients with Parkinson’s disease (PD). We aimed to investigate the effect of several assessment aspects of FOG on the quality of life (QOL) of these patients. Methods: We included 28 patients with PD in the study. FOG was assessed using the following criteria: (1) FOG questionnaire (FOGQ) items 3 and 4, (2) Gait and Falls Questionnaire (GFQ) item 14, and (3) Movement Disorder Society- Unified PD rating scale (MDS-UPDRS) Part II item 13 and Part III item 11. We also investigated the presence of FOG in common situations of actual daily living. Patients were classified into two groups based on the results of each FOG assessment. We compared the total score and values of 10 sub-items of mobility dimensions in the PD questionnaire-39 (PDQ-39) between the groups. Results: In the total score of PDQ-39, there were significant differences between the groups classified by FOGQ item 3, GFQ item 14, and MDS-UPDRS Part II item 13 and Part III item 11 but not between the groups classified by FOGQ item 4. Strong associations between the PDQ-39 sub-items (6 and 7) and the GFQ item 14 were found. Moreover, there were strong associations between the total score of PDQ-39 and the presence of FOG in common situations, such as being in crowded and cluttered places, crossing roads, and entering automatic doors. Conclusion: FOG has significant impacts on mobility-related QOL. In particular, frequency of falls due to FOG may be the major predictor of QOL. In addition, assessing the FOG occurrence in actual daily living may be valuable in promoting social participation.
Parkinson's disease
freezing of gait
quality of life

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