Departmental Bulletin Paper Distribution of Major Staphylococcal Cassette Chromosome mec Types and Exfoliative Toxin Genes in Staphylococcus pseudintermedius Strains from Dogs with Superficial Pyoderma in Japan

Kasai, Tomoko  ,  Kato, Tomoko  ,  Saegusa, Sanae  ,  Murakami, Sanae

27pp.27 - 31 , 2016-03-31 , 麻布大学 , Azabu University
Staphylococcus pseudintermedius is a major pathogen of canine pyoderma, known to produce exfoliative toxins that could be involved in formation of cutaneous lesions. To understand the genotypic distribution of S. pseudintermedius, we surveyed 74 dogs with pyoderma in three veterinary hospitals in Japan. Seventy-four S. pseudintermedius strains were isolated, 52 of which (70.3%) were mecA-positive methicillin-resistant S. pseudintermedius (MRSP). Staphylococcal cassette chromosome mec (SCCmec) typing of the identified MRSP strains revealed that the most prevalent genotype was type III-like (63.4%) followed by type V (34.6%). These data suggest high prevalence of MRSP strains consisting of two major SCCmec types among canine pyoderma in Japan. We found low prevalence of exfoliative toxin genes (exp) in the MRSP strains: expA and expB were present in 1.9% and 0%, respectively. These findings suggest no association in carriage between mecA and exp genes in S. pseudintermedius from canine pyoderma.

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