Departmental Bulletin Paper 口腔がん切除創部に対するポリグリコール酸シートとフィブリン糊スプレーとの併用被覆法(MCFP法)の有用性の検討

弘部, 悠  ,  越沼, 伸也  ,  藤居, 孝文  ,  山田, 聡  ,  渋谷, 亜佑美  ,  堀澤, 健介  ,  服部, 愛彦  ,  野井, 将大  ,  山本, 学

30 ( 1 )  , pp.108 - 111 , 2017-04-04 , 滋賀医科大学雑誌編集委員会
[Introduction] The use of polyglycolic acid (PGA) sheet and fibrin glue spray in covering resection wounds from oral surgeries have increasingly been reported. We examined the prognostic effectiveness of this treatment in our department. [Subjects and Methods] From 1 November 2010 to 31 December 2015, we investigated 26 cases in 27 sites, from the following aspects - gender, age, staging, site of the case, days to detachment of the sheet, days in use of analgesics, epithelization of wound after 30 days from surgery, postoperative bleeding, postoperative infection, and functional disorder.[Result] We examined 14 male cases, 13 female cases, and the average age of patients was 69.9 years old, with youngest patient at 48 years and the oldest at 87. Ten of the 27 cases were at Tis, 11 at Stage I, and six at Stage II. Sites of the wounds counted 22 on the tongue, two on the mandibular gingiva, one on the maxillary gingiva, one on the buccal mucosa and the last one on the floor of the mouth. In all cases the sheet became detached, on the 20.6th day on average. Analgesics were in use for the average of 13 days. All of the wounds in the 27 cases showed epithelization after 30 days from surgery. Postoperative bleeding occurred in four cases. Postoperative infection and functional disorder occurred in no cases. [Conclusion] This investigation suggests that covering resection wounds from oral surgeries with PGA sheet and fibrin glue spray is effective for soft tissue in preventing postoperative infection and functional disorder, and also in epithelization of such wounds. But We need to further investigation in regards to hard tissue.

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