紀要論文 高齢パーキンソン病患者とレジスタンス運動 : 身体機能およびメンタルヘルス,事象関連電位P300に対する影響 : 予備研究

園田, 悠馬

29 ( 1 )  , pp.14 - 20 , 2016-01-04 , 滋賀医科大学雑誌編集委員会
内容記述
Considering the aging population in Japan, an exercise program is recommended for the local elderly people. Of particular interest is the effect of muscle resistance exercise (RE) on physical and mental functions, especially in elderly patients with Parkinson disease (PD), which is characterized by the deterioration of the aforementioned functions. In a pilot study with elderly male PD patients (n = 6; age, 76.7 ± 1.86 years) at Hoehn-Yahr stage 2 or 3, we investigated the effects of an exercise program based on a BAB study design comprising muscle RE (twice a week) on motor skills, performance in activities of daily living (ADL), recognition ability, mood, and quality of life (QOL). To elucidate neurophysiological backgrounds, we analyzed changes in P300, which is a complex event-related potential induced in association with information processing. Nonparametric tests were used for statistical analysis of all data. The exercise program was shown to have selective benefits for balance ability by improving leg strength and Geriatric Depression Scale score (all p < 0.05). No significant effects were demonstrated for other measurement items, including PD symptoms or performance in ADL (Unified Parkinson’s Disease Rating Scale), cognitive function (Mini Mental State Examination), health-related QOL (36-item short-form health survey), and P300 wave. Previous reviews and meta-analyses have presented data that provide evidence to imply exercises as being beneficial to physical functioning, concurring with our findings. However, according to recent studies, rehabilitation only with simple physiotherapy is insufficient for PD patients. PD patients reportedly require intervention to reverse their mental state and lifestyle. Although this study indicated no clear improvement in ADL, cognitive function, QOL, and P300 in the PD patients that can be attributed to the exercise program with RE, occupational therapy for PD patients is obviously important to mental and physical function.
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http://repository.shiga-med.ac.jp/dspace//bitstream/10422/11133/1/jsums2901p014.pdf

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