The clinical outcome in stereotactic body radiation therapy for lung tumors
ハイ シュヨウ ニ タイスル タイカンブ テイイ ホウシャセン チリョウ ノ チリョウ セイセキ
青木, 健 ,
津川, 拓也 ,
河野, 直明村田, 喜代史
13 , 2015-12-18 , 滋賀医科大学雑誌編集委員会
Stereotactic body radiation therapy (SBRT) for lung tumors has been performed in our hospital from February 2005. We discussed the treatment outcome and the future treatment subjects of SBRT for lung tumors. In 40 cases (43 lesions) confirmed survival after SBRT for lung tumors in our hospital from Feb 2005 to Jul 2015, the average follow-up duration and the over all survival at 3 years was 26.6months and 68.1 %, respectively. In addition, local recurrence is studied by 29 cases (31 lesions) taken follow-up for computed tomography (CT) after SBRT. Local recurrence was observed in 5 cases (5 lesions) at the average of 21.0 months after SBRT. Local recurrence free survival was the average of 72.5 months. SBRT cases to lung tumors in our hospital included a fewer candidate for urgery, but were mostly inoperable. In view of this fact, treatment outcome in our hospital was comparable to the previous published reports. On local recurrence group and the local control group, we compared the changes of the appearance over or around the original tumors on follow-up CT, and measured the ratio of maximum and minimum diameter of the appearance on follow-up CT. When this ratio suddenly decreased or approached to the nearby value 1 coincided roughly with the diagnosis of local recurrence. For this reason, the variation in the ratio of maximum and minimum diameter was considered to be an aid to suggest local recurrence. By accumulating SBRT cases for lung tumors, it is necessary to evaluate the correlation with local recurrence and this ratio trend.