Departmental Bulletin Paper 複数回の抗EGFR 抗体薬投与と転移巣切除術により長期生存が得られた S 状結腸癌同時性多発肝転移の一例

園田, 文乃  ,  園田, 寛道  ,  稲富, 理  ,  目片, 英治  ,  清水, 智治  ,  塩見, 尚礼  ,  仲, 成幸  ,  谷, 眞至  ,  安藤, 朗

28 ( 1 )  , pp.40 - 44 , 2015-04-09 , 滋賀医科大学雑誌編集委員会
We report herein a case of 70-year-old man who had advanced sigmoid colon cancer with synchronous multiple liver metastases. The patient has been survived for more than six years after neoadjuvant chemotherapy with anti-EGFR antibody drugs followed by aggressive liver, lung and lymph node metastasectomy and reintroduction of anti-EGFR antibody drugs even in the inoperable state. The result observed in this case suggests that the multidisciplinary treatments combined with repeated administration of anti-EGFR antibody drugs and aggressive metastasectomy may contribute to the long-term survival for KRAS wild-type metastatic or recurrent colorectal cancer patients.

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