Journal Article Potential of electrolyzed water for disinfection of foot-and-mouth disease virus

Bui, Vuong N.  ,  Nguyen, Khong V.  ,  Pham, Nga T.  ,  Bui, Anh N.  ,  Dao, Tung D.  ,  Nguyen, Thanh T.  ,  Nguyen, Hoa T.  ,  Trinh, Dai Q.  ,  Inui, Kenjiro  ,  Uchiumi, Hiroshi  ,  Ogawa, Haruko  ,  Imai, Kunitoshi

79 ( 4 )  , pp.726 - 729 , 2017-04 , Japanese Society of Veterinary Science
ISSN:09167250
NCID:AA10796138
Description
Acidic electrolyzed water (EW) (pH 2.6-5.8) and alkaline EW (pH 11.2-12.1) were examined as potential disinfectants against foot-and-mouth disease virus (FMDV). Using acidic EW with pH 2.6 and alkaline EW with pH > 11.7, the viral titer decreased in vitro by > 4.0 log values, 2 min after the virus was mixed with EW at a 1: 10 dilution. The strong virucidal effect of acidic EW (pH 2.6), but not that of alkaline EW (> 11.7), seemed to depend on the chlorine level in the solution. Genetic analysis revealed that viral RNA was substantially reduced, especially by alkaline EW.
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