学位論文 新規NIK阻害剤mangiferinの細胞死誘導効果及びその機序の解明

武田, 朋也

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学位の種類:薬学  学位授与年月日:平成29年9月13日  主査:西田, 升三 教授  報告番号:乙第699号  学内授与番号:薬第139号Mangiferin induces apoptosis in multiple myeloma cell lines by suppressing the activation of nuclear factor kappa B-inducing kinase, Tomoya Takeda, Masanobu Tsubaki, Toshiki Kino, Misa Yamagishi, Megumi Iida, Tatsuki Itoh, Motohiro Imano, Genzoh Tanabe, Osamu Muraoka, Takao Satou, Shozo Nishida, Chemico-Biological Interactions, Volume 251, 5 May 2016, Pages 26-33, https://doi.org/10.1016/j.cbi.2016.03.018 掲載Mangiferin enhances the sensitivity of human multiple myeloma cells to anticancer drugs through suppression of the nuclear factor κB pathway, Tomoya Takeda, Masanobu Tsubaki, Toshiki Kino, Ayako Kawamura, Shota Isoyama, Tatsuki Itoh, Motohiro Imano, Genzoh Tanabe, Osamu Muraoka, Hideaki Matsuda, Takao Satou, Shozo Nishida, International Journal of Oncology, April 1, 2016 Pages:2704-2712, https://www.spandidos-publications.com/ijo/48/6/2704/abstract, https://doi.org/10.3892/ijo.2016.3470 掲載Mangiferin, a novel nuclear factor kappa B-inducing kinase inhibitor, suppresses metastasis and tumor growth in a mouse metastatic melanoma model, Tomoya Takeda, Masanobu Tsubaki, Kotaro Sakamoto, Eri Ichimura, Aya Enomoto, Yuri Suzuki, Tatsuki Itoh, Motohiro Imano, Genzoh Tanabe, Osamu Muraoka, Hideaki Matsuda, Takao Satou, Shozo Nishida, Toxicology and Applied Pharmacology, Volume 306, 1 September 2016, Pages 105-112, https://doi.org/10.1016/j.taap.2016.07.005 掲載
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