学術雑誌論文 ACOUSTIC RADIATION FORCE IMPULSE ELASTOGRAPHY FOR THE DIFFERENTIAL DIAGNOSIS OF LIVER TUMORS IN PATIENTS WITH LIVER DYSFUNCTION

CHIBA, Mitsuru  ,  GOTO, Takashi  ,  OHSHIMA, Shigetoshi  ,  MIURA, Kouichi  ,  SHIBUYA, Tomomi  ,  SATO, Wataru  ,  DOHMEN, Takahiro  ,  SEKINE, Masanari  ,  KANATA, Ryo  ,  SAKAI, Toshitaka  ,  MINAMI, Shinichiro  ,  FUJITA, Akashi  ,  OHNISHI, Hirohide

42 ( 1 )  , pp.19 - 27 , 2015-06-30 , 秋田医学会
ISSN:03866106
NII書誌ID(NCID):AN00009294
内容記述
Objective : Acoustic radiation force impulse (ARFI) technology can measure the elasticity of tissueand tumor. The aim of this study was to evaluate whether the ARFI technology can differentiatecavernous hemangioma, hepatocellular carcinoma (HCC) and metastatic liver tumors inpatients with liver dysfunction.Materials and Methods : Forty patients with liver dysfunction and liver tumors were enrolledin the study. The shear wave velocities (SWVs) in the tumors and background liver were examinedby ARFI elastography under ultrasonography (US).Results : The SWVs in livers bearing HCCs were significantly higher than those of livers bearingcavernous hemangiomas. The SWVs in HCCs and metastatic liver tumors were significantlyhigher than those in cavernous hemangiomas. The SWVs in metastatic liver tumors were significantlyhigher than those in HCCs. The SWV ratio of metastatic liver tumor/parenchyma wassignificantly higher than that of cavernous hemangioma/parenchyma and HCC/parenchyma.There was a significant correlation between the tumor sizes and the SWVs in metastaticliver tumors.Conclusions : We herein demonstrated that ARFI elastography could noninvasively provide helpfulinformation, without the need for biopsy, that could be used for the differential diagnosis amongcavernous hemangiomas, HCCs and metastatic liver tumors in patients with liver dysfunction.
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http://air.lib.akita-u.ac.jp/dspace/bitstream/10295/2908/3/akitai42-1%2819%29.pdf

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