学位論文 新規緑内障治療薬リパスジル開発における薬物動態および房水動態解析

磯部, 友之

2017-03-01
内容記述
富山大学・富医薬博甲第237号・磯部 友之・2017/03/01
This doctoral thesis summarizes the full contents of the following publications. 1)Species differences in metabolism of ripasudil (K-115) are attributed to aldehyde oxidase This is an Accepted Manuscript of an article published by Taylor & Francis in Xenobiotica on 18/12/2015, available online: http://www.tandfonline.com/10.3109/00498254.2015.1096981.2)Effects of K-115, a Rho-Kinase Inhibitor, on Aqueous Humor Dynamics in Rabbits This is an Accepted Manuscript of an article published by Taylor & Francis in Current Eye Research on 06/02/2014, available online: http://www.tandfonline.com/10.3109/02713683.2013.874444.3)Ocular Penetration and Pharmacokinetics of Ripasudil Following Topical Administration to Rabbits Final publication is available from Mary Ann Liebert, Inc., publishers http://dx.doi.org/10.1089/jop.2016.0028.
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