学術雑誌論文 Levels of polychlorinated dibenzodioxins and polychlorinated dibenzofurans in breast milk samples from three dioxin-contaminated hotspots of Vietnam

Manh, Ho Dung  ,  Kido, Teruhiko  ,  Tai, Pham The  ,  Okamoto, Rie  ,  Honma, Seijiro  ,  Liang, Sun Xian  ,  Anh, Le Thai  ,  Maruzeni, Shoko  ,  Nghi, Tran Ngoc  ,  Nishijo, Muneko  ,  Nakagawa, Hideaki  ,  Nhu, Dang Duc  ,  Tung, Dao Van  ,  Hung, Nguyen Ngoc  ,  Son, Le Ke

511pp.416 - 422 , 2015-04-01 , Elsevier
ISSN:0048-9697
NII書誌ID(NCID):AA00836666
内容記述
We determined polychlorinated dibenzodioxin (PCDD) and polychlorinated dibenzofuran (PCDF) levels in breast milk of 143 primiparae living around the three most dioxin-contaminated areas of Vietnam. The women sampled lived in the vicinity of former U.S. air bases at Bien Hoa (n. =. 51), Phu Cat (n. =. 23), and Da Nang (n. =. 69), which are known as dioxin hotspots. Breast milk samples from Bien Hoa City, where residents live very close to the air base, showed high levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), with 18% of the samples containing >. 5. pg. TCDD/g lipid. However, Phu Cat residents lived far from the air base and their samples showed lower TCDD levels, with none containing >. 5. pg. TCDD/g lipid. In Da Nang, TCDD levels in mothers from Thanh Khe (close to the air base, n. =. 43) were significantly higher than those in mothers from Son Tra (far from the air base, n. =. 26), but not other PCDD and PCDF (PCDD/F) congeners. Although TCDD levels in Bien Hoa were the highest among these hotspots, levels of other PCDD/F congeners as well as the geometric mean concentration of total PCDD/F level in Bien Hoa (9.3. pg toxic equivalents [TEQ]/g lipid) were significantly lower than the level observed in Phu Cat (14.1. pg. TEQ/g lipid), Thanh Khe (14.3. pg. TEQ/g lipid), and Son Tra (13.9. pg. TEQ/g lipid). Our findings indicated that residents living close to former U.S. air bases were exposed to elevated levels of TCDD, but not of other PCDD/F congeners.
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http://dspace.lib.kanazawa-u.ac.jp/dspace/bitstream/2297/40614/1/ME-PR-KIDO-T-416.pdf

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