学術雑誌論文 Membrane vesicle-mediated bacterial communication

Toyofuku, Masanori  ,  Morinaga, Kana  ,  Hashimoto, Yohei  ,  Uhl, Jenny  ,  Shimamura, Hiroko  ,  Inaba, Hideki  ,  Schmitt-Kopplin, Philippe  ,  Eberl, Leo  ,  Nomura, Nobuhiko

11 ( 6 )  , pp.1504 - 1509 , 2017-06 , Nature Publishing Group
ISSN:1751-7362
NII書誌ID(NCID):AA12230488
内容記述
The classical quorum-sensing (QS) model is based on the assumption that diffusible signaling molecules accumulate in the culture medium until they reach a critical concentration upon which expression of target genes is triggered. Here we demonstrate that the hydrophobic signal N-hexadecanoyl-L-homoserine lactone, which is produced by Paracoccus sp., is released from cells by the aid of membrane vesicles (MVs). Packed into MVs, the signal is not only solubilized in an aqueous environment but is also delivered with varying propensities to different bacteria. We propose a novel MV-based mechanism for binary trafficking of hydrophobic signal molecules, which may be particularly relevant for bacteria that live in open aqueous environments.
本文を読む

https://tsukuba.repo.nii.ac.jp/?action=repository_action_common_download&item_id=41463&item_no=1&attribute_id=17&file_no=1

このアイテムのアクセス数:  回

その他の情報