||Hemostasis management of tooth extraction in a patient with Bernard–Soulier syndrome and a severe bleeding tendency: A case report
Mishima, Sayaka ,
Nakao, Kazumasa ,
Ikeno, MasayukiBessho, Kazuhisa
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
528 , 2015-07 , Elsevier Japan KK
Bernard–Soulier syndrome is characterized by thrombocytopenia, giant platelets, and severe bleeding; although bleeding varies widely, it is usually evident from childhood and requires particular attention during surgeries. We extracted a fractured tooth and performed hemostasis management in a male patient with a Bernard–Soulier syndrome-related severe bleeding tendency after intracerebral hemorrhage. The preoperative platelet count was abnormally low (7 × 10/L). Normal coagulability was observed. After intravenous hydrocortisone administration, he received 10 human leukocyte antigen-matched platelet units. The extraction sites were packed with gelatine sponges and a splint was used for hemostasis. Excellent hemostasis was achieved with minimal human leukocyte antigen-matched platelets.