||Benzyllithiums bearing aldehyde carbonyl groups. A flash chemistry approach.
Nagaki, Aiichiro ,
Tsuchihashi, Yuta ,
Haraki, SuguruYoshida, Jun-ichi
Organic & biomolecular chemistry
7145 , 2015-06-09 , Royal Society of Chemistry
Accepted 21 May 2015
Reductive lithiation of benzyl halides bearing aldehyde carbonyl groups followed by reaction with subsequently added electrophiles was successfully accomplished without affecting the carbonyl groups by taking advantage of short residence times in flow microreactors.