||Palladium-catalyzed formal hydroacylation of allenes employing carboxylic anhydrides and hydrosilanes
Fujihara, Tetsuaki ,
Hosomi, Takuro ,
Cong, Cong ,
Hosoki, Tomoya ,
Terao, JunTsuji, Yasushi
4574 , 2015-07-01 , Elsevier Ltd.
The formal hydroacylation reaction of allenes has been developed employing carboxylic anhydrides as acyl sources and hydrosilanes as reducing reagents in the presence of a commercially available palladium complex as a catalyst. The reaction affords α, β-unsaturated ketones regio- and stereoselectively. The similar catalyst system is also effective for the reduction of carboxylic anhydrides to the corresponding aldehydes employing hydrosilanes.