||Significance of Intraoral Elastography in the Evaluation of Muscular Invasion of Early-stage Tongue Carcinoma
Shingaki, Motoki新垣, 元基
学位の種類: 博士（歯学）. 報告番号: 甲第4146号. 学位記番号: 新大院博（歯）甲第344号. 学位授与年月日: 平成28年3月23日
Objective. Cervical lymph node metastasis is the most important prognostic factor in patients with tongue carcinoma. Several studies advocate that the muscular invasion of the primary tumor significantly relates to cervical lymph node metastasis. Elastography is an ultrasonographic technology that enables visualization of tissue elasticity. In this preliminary study, we estimated the usefulness of intraoral elastography for the evaluation of muscular invasion of early-stage tongue carcinoma by comparison between preoperative elastography and histopathological findings. Study Design. Twenty five patients with early-stage tongue carcinomas (Tis, T1, T2) were included (10 females and 15 males; age range 38–85 years). Preoperative intraoral ultrasonography was performed with an intraoperative probe. We evaluated the differences in margins between the hypoechoic tumorous area on B-mode images and the blue hard area on elastographic images. Results. Among 20 cases with muscular invasion, exudation of the blue hard area around the margin of the hypoechoic tumorous area was observed. In contrast, in five cases with non-invasive carcinoma, the margins of the hard area corresponded almost exactly with those of the hypoechoic tumorous area. Conclusions. Although the present study included a limited number of cases, it was suspected that intraoral elastography is a promising method to evaluate the muscular invasion of tongue carcinoma.