学術雑誌論文 Significance of High-frequency Electrical Brain Activity

Kobayashi, Katsuhiro  ,  Akiyama, Tomoyuki  ,  Agari, Takashi  ,  Sasaki, Tatsuya  ,  Shibata, Takashi  ,  Hanaoka, Yoshiyuki  ,  Akiyama, Mari  ,  Endoh, Fumika  ,  Oka, Makio  ,  Date, Isao

71 ( 3 )  , pp.191 - 200 , 2017-06 , Okayama University Medical School
ISSN:0386-300X
NII書誌ID(NCID):AA00508441
内容記述
 Electroencephalogram (EEG) data include broadband electrical brain activity ranging from infra-slow bands (< 0.1 Hz) to traditional frequency bands (e.g., the approx. 10 Hz alpha rhythm) to high-frequency bands of up to 500 Hz. High-frequency oscillations (HFOs) including ripple and fast ripple oscillations (80-200 Hz and>200 / 250 Hz, respectively) are particularly of note due to their very close relationship to epileptogenicity, with the possibility that they could function as a surrogate biomarker of epileptogenicity. In contrast, physiological high-frequency activity plays an important role in higher brain functions, and the differentiation between pathological / epileptic and physiological HFOs is a critical issue, especially in epilepsy surgery. HFOs were initially recorded with intracranial electrodes in patients with intractable epilepsy as part of a long-term invasive seizure monitoring study. However, fast oscillations (FOs) in the ripple and gamma bands (40-80 Hz) are now noninvasively detected by scalp EEG and magnetoencephalography, and thus the scope of studies on HFOs /FOs is rapidly expanding.
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http://ousar.lib.okayama-u.ac.jp/files/public/5/55201/20170614134530879338/71_3_191.pdf

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