Journal Article カフェインによるアレルギー性鼻炎の抑制効果

辻本, まどか  ,  佐伯, 綾希子  ,  鈴木, 真奈美  ,  白神, 俊幸  ,  杉本, 幸雄  ,  林, 泰資

33pp.18 - 21 , 2017-04 , 岡山実験動物研究会
We examined the effects of caffeine treatment on ovalbumin- and histamine-induced rhinitis mouse models and on corticosterone and catecholamine levels in mouse plasma. Treatment with caffeine decreased sneezing and nasal rubbing in both models, but direct nasal administration had no effect. Plasma levels of corticosterone and catecholamine, which have known anti-allergy effects, were increased by caffeine treatment. The increases in corticosterone and catecholamine may be associated with the suppression of rhinitis symptoms.

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