Journal Article 原発性十二指腸粘液癌の一例― 本邦報告16例の検討―
A case of mucinous adenocarcinoma of the duodenum and literature review of 16 cases reported in Japan

浜野, 郁美  ,  松本, 祐介  ,  遠藤, 芳克  ,  渡邊, 直樹  ,  甲斐, 恭平  ,  佐藤, 四三  ,  和仁, 洋治

128 ( 1 )  , pp.21 - 25 , 2016-04-01 , 岡山医学会
 Primary mucinous adenocarcinoma of the duodenum is rare. Here we report a case we recently encountered, and we review 16 cases reported in Japan. An 82-year-old Japanese woman was admitted to our hospital complaining of abdominal pain and heartburn. An endoscopic examination revealed a Type 2 tumor in the descending limb of the duodenum, and endoscopically obtained specimens revealed a poorly differentiated adenocarcinoma. We performed a curative pancreatoduodenectomy with lymph node resection, and the surgical specimen revealed that the duodenum was the primary site of the mucinous adenocarcinoma. The patient is currently alive > 1 year after the operation without any evidence of recurrence. Of the 16 patients reviewed, all patients had advanced tumors those depth were T3-T4. 9 patients had lymph node metastasis and 4 patients had peritoneal dissemination at the time of surgery. Since mucinous adenocarcinoma of the duodenum is often progressive cancer at a diagnosis, which is tend to have a worse prognosis than other histological types.

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