Journal Article A Long-term Survivor after Congenital Acute Myeloid Leukemia with t(8 ; 16)(p11 ; p13)

Hanada, Takae  ,  Kanamitsu, Kiichiro  ,  Chayama, Kosuke  ,  Miyamura, Takako  ,  Kanazawa, Yui  ,  Muraoka, Michiko  ,  Washio, Kana  ,  Imada, Masahide  ,  Kageyama, Misao  ,  Takeuchi, Akihito  ,  Tamai, Kei  ,  Oda, Megumi  ,  Shimada, Akira

70 ( 1 )  , pp.31 - 35 , 2016-02 , Okayama University Medical School
The treatment of patients with congenital leukemia is difficult and often results in a poor prognosis. We present here the case of a female child with congenital acute myeloid leukemia (AML) with t(8 ; 16) (p11 ; p13) who received chemotherapy and survived for more than 10 years without relapse. A novel MOZ-CBP chimera was found in her diagnostic sample. Although adult AML patients with MOZ-CBP have mainly been reported as having therapy-related AML and showed poor prognoses, the present case supports the idea that AML with MOZ-CBP in the pediatric population might show better prognoses.

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