Journal Article Pure Choriocarcinoma of the Ovary in Silver-Russell Syndrome

Haruma, Tomoko  ,  Ogawa, Chikako  ,  Nishida, Takeshi  ,  Kusumoto, Tomoyuki  ,  Nakamura, Keiichiro  ,  Seki, Noriko  ,  Katayama, Takaaki  ,  Hiramatsu, Yuji

69 ( 3 )  , pp.183 - 188 , 2015-06 , Okayama University Medical School
Pure ovarian choriocarcinoma is an extremely rare malignancy that can be gestational or non-gestational in origin. Silver-Russell syndrome (SRS) is a rare congenital developmental disorder characterized by pre- and postnatal growth failure, relative macrocephaly, a triangular face, hemihypotrophy, and fifth-finger clinodactyly. We report a rare case of pure ovarian choriocarcinoma occurring in a 19-year-old woman with SRS. Following surgery, multiple chemotherapy courses were effective and she was free of disease at the 10-month follow-up.

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