Thesis or Dissertation Health-related Quality of Life and Potential Barriers to

Irie, Yuki  ,  Hayashi, Kunihiko  ,  Shinozaki, Hiromitsu

67 ( 4 )  , pp.291 - 298 , 2017-11-01 , 北関東医学会
Background and aims:Malnutrition is common in hemodialysis (HD) patients, which is known to reduce theirhealth-related quality of life(QOL). Potential barriers to adequate nutrition can affect a patient’s nutritional status,although whether they also affect the patient’s QOL remains unclear. This study investigated the associationsbetween several potential barriers and QOL among HD patients. M ethods:This cross-sectional study included 36Japanese patients receiving HD for 3 months. The patients completed structured questionnaires regarding anypotential barriers to adequate nutrition. Clinical parameters were evaluated during monthly check-ups. Results:The presence of 1 potential barrier significantly associated with decreased scores in the effect of kidney disease,burden of kidney disease, cognitive function, quality of social interaction, and mental health subscales in theKidney Disease Quality of Life Short Form. Poor knowledge was the most common potential barrier to adequatenutrition. However, difficulty chewing was significantly associated with the greatest number of decreased QOLsubscale scores, even after adjustment for age, suggesting that this barrier has the greatest direct effect on QOL.Conclusions: The presence of 1 potential barrier significantly associated with reduced QOL, indicating theimportance of evaluating potential barriers to adequate nutrition. Further study is necessary to investigate thepossibility that assessment and managing potential barriers improve QOL of patients receiving HD.

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