学術雑誌論文 Pheochromocytoma multisystem crisis treated with emergency surgery: a case report and literature review

Kakoki, Katsura  ,  Miyata, Yasuyoshi  ,  Shida, Youhei  ,  Hakariya, Tomoaki  ,  Takehara, Kosuke  ,  Izumida, Seiya  ,  Sekino, Motohiro  ,  Kinoshita, Naoe  ,  Igawa, Tsukasa  ,  Fukuoka, Junya  ,  Sakai, Hideki

8p.758 , 2015-12-09 , BioMed Central
内容記述
Background: Pheochromocytoma is a neuroendocrine tumor that predominantly presents with hypertension, palpitations, and tachycardia due to excessive catecholamine excretion. Although pheochromocytoma multisystem crisis (PMC) is relatively rare, urologists and clinicians should focus on early diagnosis as delay in initiating the appropriate treatment can lead to mortality Case presentation: A 70-year-old man developed ileus after a few days of medication for hypertension. Computed tomography incidentally revealed a left adrenal mass. This finding together with his clinical course was compatible with pheochromocytoma. An α-blocker was administered immediately, and his blood pressure was well controlled. However, his general condition and laboratory data deteriorated rapidly, and the patient was diagnosed with PMC with lethal status. Thus, emergency adrenalectomy was performed without confirmation of catecholamine levels. From the resected specimen, his tumor was judged as pheochromocytoma. On immunohistochemical analysis, the proliferation index evaluated by Ki-67 staining was 9.7 %. This case report was approved by the Human Ethics Review Committee of the Nagasaki University Hospital. Conclusion: The present case of PMC was successfully treated with emergency surgery. The benign pheochromocytoma also presented with high cell proliferation potential, which may be a cause of the extreme aggressiveness of PMC.
本文を読む

http://naosite.lb.nagasaki-u.ac.jp/dspace/bitstream/10069/36133/1/BMCRN8_758.pdf

このアイテムのアクセス数:  回

その他の情報