Journal Article A MULTI-GROUP SIR EPIDEMIC MODEL WITH AGE STRUCTURE

Kuniya, Toshikazu  ,  Wang, Jinliang  ,  Inaba, Hisashi

21 ( 10 )  , pp.3515 - 3550 , 2016-12 , American Institute of Mathematical Sciences (AIMS)
ISSN:153134921553524X
Description
Published online: November 2016. This paper provides the first detailed analysis of a multi-group SIR epidemic model with age structure, which is given by a nonlinear system of 3n partial differential equations. The basic reproduction number R-0 is obtained as the spectral radius of the next generation operator, and it is shown that if R-0 < 1, then the disease-free equilibrium is globally asymptotically stable, while if R-0 > 1, then an endemic equilibrium exists. The global asymptotic stability of the endemic equilibrium is also shown under additional assumptions such that the transmission coefficient is independent from the age of infective individuals and the mortality and removal rates are constant. To our knowledge, this is the first paper which applies the method of Lyapunov functional and graph theory to a multi-dimensional PDE system.
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