Departmental Bulletin Paper Thrombospondin 1 Suppresses Insulin Signaling in C2C12 Myotubes

Matsugi, Kaku  ,  Hosooka, Tetsuya  ,  Nomura, Kazuhiro  ,  Ogawa, Wataru

62 ( 1 )  , pp.13 - 18 , 2016 , 神戸大学医学部
ISSN:00232513
NCID:AA00711740
Description
Thrombospondin 1 (TSP-1) is abundantly expressed in visceral adipose tissue and this expression is up-regulated in obese humans and rodents. Recent studies showed that genetic deletion of TSP-1 protects mice from diet-induced insulin resistance. However,
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