Journal Article Coherent anti-Stokes Raman scattering rigid endoscope toward robot-assisted surgery

Hirose, Keigo  ,  Aoki, Takuya  ,  Furukawa, Taichi  ,  Fukushima, Syuichirou  ,  Niioka, Hirohiko  ,  Deguchi, Shinji  ,  Hashimoto, Mamoru

9 ( 2 )  , pp.387 - 396 , 2018-02-01 , The Optical Society
Label-free visualization of nerves and nervous plexuses will improve the preservation of neurological functions in nerve-sparing robot-assisted surgery. We have developed a coherent anti-Stokes Raman scattering (CARS) rigid endoscope to distinguish nerves from other tissues during surgery. The developed endoscope, which has a tube with a diameter of 12 mm and a length of 270 mm, achieved 0.91% image distortion and 8.6% non-uniformity of CARS intensity in the whole field of view (650 μm diameter). We demonstrated CARS imaging of a rat sciatic nerve and visualization of the fine structure of nerve fibers.

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