学術雑誌論文 Isolation of a simian immunodeficiency virus from a malbrouck (Chlorocebus cynosuros)

Carr, Michael  ,  Kawaguchi, Akira  ,  Sasaki, Michihito  ,  Gonzalez, Gabriel  ,  Ito, Kimihito  ,  Thomas, Yuka  ,  Hang'ombe, Bernard M.  ,  Mweene, Aaron S.  ,  Zhao, Guoyan  ,  Wang, David  ,  Orba, Yasuko  ,  Ishii, Akihiro  ,  Sawa, Hirofumi

162 ( 2 )  , pp.543 - 548 , 2016-11-01 , Springer
ISSN:0304-8608
内容記述
To investigate the diversity of simian immunodeficiency virus (SIV) among nonhuman primates (NHPs) in Zambia, next-generation sequencing was performed to determine the complete genome sequence of a novel SIV recovered by co-culturing African green monkey (AGM) peripheral blood lymphocytes with human CD4(+) T-cell lines. We report the first described SIV (SIVagmMAL-ZMB) from a malbrouck (Chlorocebus cynosuros). SIVagmMAL-ZMB was detected by real-time PCR analysis of splenic RNA in 3.2% (3/94) of AGMs and was undetectable in baboons (0/105). SIVagmMAL-ZMB possessed < 80% nucleotide sequence identity to known SIV isolates and was located basally to vervet monkey SIV strains in all phylogenies.
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https://eprints.lib.hokudai.ac.jp/dspace/bitstream/2115/67556/1/%2877624%29Isolation%20of%20a%20Simian%20Immunodeficiency%20Virus%20from%20the%20Malbrouck%20%28Chloroc....pdf

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