||Iodofluorination of Alkenes Using IF5-Pyridine-HF
Yano, ShoheiHara, Shoji
2843 , 2015-09 , Georg Thieme Verlag
Iodofluorination of alkenes was performed by using IF5-pyridine-HF and a reductant such as potassium iodide or tin powder. The addition of IF to the double bond proceeded with stereo- and regioselectivity. In the reaction with internal alkenes, the trans-addition product was obtained selectively. With terminal alkenes, the addition took place regioselectively to give 1-iodo-2-fluoroalkanes.