Synthesis of Diazirine-Based Photoreactive Saccharin Derivatives for the Photoaffinity Labeling of Gustatory Receptors

Wang, Lei; Yoshida, Takuma; Muto, Yasuyuki; Murai, Yuta; Tachrim, Zetryana Puteri; Ishida, Akiko; Nakagawa, Shiori; Sakihama, Yasuko; Hashidoko, Yasuyuki; Masuda, Katsuyoshi; Hatanaka, Yasumaru; Hashimoto, Makoto

Synthesis of Diazirine-Based Photoreactive Saccharin Derivatives for the Photoaffinity Labeling of Gustatory Receptors

"/Wang, Lei/"Wang, Lei , "/Yoshida, Takuma/"Yoshida, Takuma , "/Muto, Yasuyuki/"Muto, Yasuyuki , "/Murai, Yuta/"Murai, Yuta , "/Tachrim, Zetryana Puteri/"Tachrim, Zetryana Puteri , "/Ishida, Akiko/"Ishida, Akiko , "/Nakagawa, Shiori/"Nakagawa, Shiori , "/Sakihama, Yasuko(1000010344491)/"Sakihama, Yasuko , "/Hashidoko, Yasuyuki(1000040281795)/"Hashidoko, Yasuyuki , "/Masuda, Katsuyoshi(1000030190359)/"Masuda, Katsuyoshi , "/Hatanaka, Yasumaru(1000030111181)/"Hatanaka, Yasumaru , "/Hashimoto, Makoto(1000090292094)/"Hashimoto, Makoto

European journal of organic chemistry

(14) , pp.3129 - 3134 , 2015-05-18 , Wiley-Blackwell

ISSN:1434-193X

内容記述

Saccharin is one of the most common artificial sweeteners that has a bitter taste at high concentrations. Currently, there are no detailed functional analyses of these gustatory receptors. Therefore, we designed and synthesized photoreactive saccharin derivatives that contain a (trifluoromethyl) diazirinyl moiety at the 5- or 6-position for use as functional analysis tools for photoaffinity labeling.

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https://eprints.lib.hokudai.ac.jp/dspace/bitstream/2115/61529/1/70112%28hashimoto%ef%bc%89.pdf

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その他の情報

著者キーワード	Synthetic methods Photoaffinity labeling Receptors Nitrogen heterocycles Saccharin
公開者	Wiley-Blackwell
国立情報学研究所メタデータ主題語彙集（資源タイプ）	Journal Article
フォーマット	application/pdf
言語	eng
DOI	info:doi/10.1002/ejoc.201500184
権利	The right to self-archive the accepted and peer-reviewed(but not final) version of the Contribution on the Contributor’s personal website, in the Contributor’s company/institutional repository or archive, and in certain not for profit subject-based repositories such as PubMed Central, subject to an embargo period of 12 months following publication of the final Contribution.
著者版フラグ	author
日本十進分類法	460
URL	http://jairo.nii.ac.jp/0003/00049463

Synthesis of Diazirine-Based Photoreactive Saccharin Derivatives for the Photoaffinity Labeling of Gustatory ReceptorsSynthesis of Diazirine-Based Photoreactive Saccharin Derivatives for the Photoaffinity Labeling of Gustatory Receptors

Synthesis of Diazirine-Based Photoreactive Saccharin Derivatives for the Photoaffinity Labeling of Gustatory Receptors